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Thursday, July 26, 2007

Interleukin Genetics Initiates Program To Develop Genetic Test To Guide More Effective Weight Control In Obese Patients

Welcome to the Brave New World of weight loss.

This is where lies, technobabble and hope intersect with hype.

Here are lies and technobabble:
"Obesity is basically an excessive storage of triglycerides in fat (adipose) tissue. Although the biological mechanisms involved in storage and release of triglycerides in adipose tissue are poorly understood, a family of proteins, including the perilipin protein, regulate triglyceride release under certain conditions. If the perilipin protein is eliminated in mice, i.e. the "knockout model," the mice have altered fat metabolism, a lean body type, and are resistant to weight gain even in the presence of over-feeding a high-fat diet...

Studies indicate that 20-70% of the weight differences among people are due to genetics, and more than 60% of the weight gain during middle age is attributable to genetic factors. Most importantly, the amount of weight gain that results from over-eating has a major genetic component."
Lie:

Obesity is NOT "basically an excessive storage of triglycerides in fat (adipose) tissue." It is storage of excessive Calories that are consumed. There is no excessive storage, you simply store the Calories that you do not burn.

Lie:

"...the amount of weight gain that results from over-eating has" NO "major genetic component." All overeaten Calories must be stored, they have nowhere else to go.

There are more.

How do you know that their assertions are bull and hype? Here is their disclaimer:
"Certain statements contained herein are "forward-looking" statements including statements regarding our ability to develop genetic tests based upon our perilipin genetic technology , develop diagnostic, personalized nutritional and therapeutic products to prevent or treat diseases of inflammation and other genetic variations, our ability to screen nutritional compounds for their effects on inflammatory responses and other genetic variations, given specific genetic patterns and our ability to make progress in advancing our core technologies. Because such statements include risks and uncertainties, actual results may differ materially from those expressed or implied by such forward-looking statements. Factors that could cause actual results to differ materially from those expressed or implied by such forward- looking statements include, but are not limited to, the risk of market acceptance of our products, the risk of technology and product obsolescence, delays in product development, our ability to identify appropriate commercial partners and enter into favorable arrangements with them, the performance of our commercial partners, the availability of adequate capital, the actions of our competitors and other competitive risks, and those risks and uncertainties described in our annual report on Form 10-K for the year ended December 31, 2006, as amended, filed with the Securities and Exchange Commission, our quarterly reports on Form 10-Q and other filings made by us with the Securities and Exchange Commission. We disclaim any obligation or intention to update these forward-looking statements."

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