Protein That Slows Aging May Protect Against Diabetes

Much easier to not eat a high-fat diet than it is for the sick care system to develop more invasive treatments (if ever).

A new MIT study has found that a protein that slows aging in mice and other animals also helps fight against the damages of a high-fat diet, including diabetes.

Over a decade ago, SIRT1's longevity-boosting properties were discovered by MIT biology professor Leonard Guarente, who has continued to examine its role in various body tissues. His recent study, appearing August 8th in the journal Cell Metabolism, observed what happens when the SIRT1 protein is missing from adipose cells, which make up body fat.

The research team put mice on a high-fat diet and realized that they started to develop metabolic disorders, like diabetes, when they lacked the protein, while normal mice given the same diet did not develop these disorders as quickly.

Guarente, the Novartis Professor of Biology at MIT, explained: "We see them as being poised for metabolic dysfunction. You've removed one of the safeguards against metabolic decline, so if you now give them the trigger of a high-fat diet, they're much more sensitive than the normal mouse."

This finding suggests that drugs that enhance SIRT1 activity could possibly help fight against obesity-linked diseases.

But they won't and they will have side effects.

Physically Fit Boys And Girls Score Higher On Reading And Math

More fat kids are stupider than intended-sized kids.

Having a healthy heart and lungs may be one of the most important factors for middle school students to make good grades in math and reading, according to findings presented at the American Psychological Association's 120th Annual Convention.

"Cardiorespiratory fitness was the only factor that we consistently found to have an impact on both boys' and girls' grades on reading and math tests," said study co-author Trent A. Petrie, PhD, professor of psychology and director of the Center for Sport Psychology at the University of North Texas.

"This provides more evidence that schools need to re-examine any policies that have limited students' involvement in physical education classes."

PE classes will not do squat.

Crappy parents will continue to overfeed their kids.

Holding parents accountable for what they do to their kids is what it will take.

Guess the researchers are fat since they are so stupid.

Weight training 'reduces diabetes risk'

Almost certainly true.

Weight training helps to prevent type 2 diabetes in men, research suggests.

Researchers found regular weights reduced the risk by up to a third, in the study of more than 32,000 men published in the Archives of Internal Medicine journal. It is already well known that regular exercise can prevent the disease.

But the report is considered important as weights provides an alternative to aerobic exercises such as running for people who are not so mobile.

Researchers from Harvard School of Public Health in the US and the University of Southern Denmark followed the men over an 18-year period, during which time nearly 2,300 developed the condition.

'Difficulty' They found 30 minutes of weights a day, five times a week could reduce the risk of diabetes by 34%. But they also reported that even less regular exercise - up to an hour a week - had an impact, cutting the risk by 12%.

Nonetheless, aerobic exercise was still found to be slightly better with regular activity halving the risk.

But they are wrong in that the training must be done properly or it will have no real effect, or even a negative one.

This happens when people fool themselves into believing that their paltry efforts can be effective.

They will not.

To learn how to train, go here.

Fracture Risk Not Found To Increase Following Bariatric Surgery

No, the news is not good.

An international study, led by researchers at the Medical Research Council Lifecourse Epidemiology Unit (MRC LEU) at the University of Southampton, has found that obese patients who undergo bariatric surgery are not at an increased risk of broken bones in the first few years after the operation.

However, the study, published in the British Medical Journal has shown that there is a possibility of an increase in fracture risk after three to five years.

Generally, a higher Body Mass Index (BMI) protects the bone against most types of fracture because a higher BMI is associated with increased bone density. Additionally there is more protection around the bones.

Studies have shown that weight loss can lead to a reduction of bone density and specifically studies have suggested that bone density is lost after bariatric surgery; however no previous work has been able to investigate whether such changes might result in an increased risk of fracture relative to a control population.

Just lose the weight naturally.

Here is how.

Chronic Diseases May Stem From Bacteria-Immune System 'Fight'

Must be these guys:



Not this:

Results from a study conducted at Georgia State University suggest that a "fight" between bacteria normally living in the intestines and the immune system, kicked off by another type of bacteria, may be linked to two types of chronic disease. The study suggests that the "fight" continues after the instigator bacteria have been cleared by the body, according to Andrew Gewirtz, professor of biology at the GSU Center for Inflammation, Immunity and Infection. That fight can result in metabolic syndrome, an important factor in obesity, or inflammatory bowel disease (IBD).

There can be no other explanation.

50% Of UK Adults Don't Think They Can Run 100 Meters

And they are probably 100% right.

Jamaica's Usain Bolt won the Olympic 100 metres in 9.63 seconds on Sunday, reaching a peak speed of around 23mph in a dazzling display of athletic sprinting. On the flip side of that, a survey released this week has revealed that around 45% of adults believe they would be unable to run 100 meters without stopping.

To mark the start of Slimming World's Miles for SMILES activity program, a program that promotes physical activity whilst raising money for the NSPCC, Slimming World together with YouGov conducted a survey involving 2,065 people, which discovered that 56% of women believed they would find it hard or impossible to run 100 meters compared with 31% of men.

The announcement of London hosting the Olympics was thought to encourage Brits to become more active. However, the survey showed that 75% of people, i.e. three out of four individuals are never physically competitive active, whilst over half, i.e. 55% are not physically active at all. In contrast, 6 out of 10 men or 59% enjoy watching sport on TV at least once every week, which is likely to increase during the Olympics.

Not SMILES.

SFB = Sh*t For Brains.

That is what you must have to think that these "initiatives" will work. Morons.

Food Addiction, Obesity And The Lasting Health Benefits Of Modest Weight Loss

Another reason not to pay for a fat person's illnesses of choice.

Overweight and obese individuals can achieve a decade's worth of important health benefits by losing just 20 pounds, even if they regain the weight later that decade, according to research presented at the American Psychological Association's 120th Annual Convention.

The time to start stopping is now.

Fiber-Added Foods May Not Stem Hunger

Of course not.

Fiber-enriched processed foods promise a healthier version of snacks, but they might not keep hunger at bay, a small study suggests. The researchers found no hunger-limiting effects of chocolate bars containing four different "functional fibers," such as inulin - aka "chicory root extract" - commonly found in fiber-enriched processed foods.

Overall, the women in the study were just as hungry come lunch time as they were on a day when they ate a low-fiber bar for breakfast. And their food intake for the rest of the day was similar as well.

There is more to the sensation of hunger than the feeling of fullness. No surprise here.

Gut Bacteria During Pregnancy Mimic Metabolic Syndrome

Nutso. Not so.

The composition of microbes in the gut changes dramatically during pregnancy, and although these changes are normally associated with metabolic syndrome, they could be beneficial in pregnant women.

Omry Koren, PhD, from the Department of Microbiology and Department of Molecular Biology and Genetics at the University of Colorado in Boulder, and colleagues published their findings in the August 3 issue of Cell.

According to the researchers, several studies suggest a role for "gut microbiota in driving metabolic disease, including inflammation, weight gain, and reduced insulin sensitivity."

Likewise, during pregnancy, bacterial load is reported to increase; however, "a comprehensive view of how microbial diversity changes over the course of normal pregnancy is lacking."

"The contribution of intestinal host-microbial interactions in promoting weight gain and other metabolic changes in the context of pregnancy remains to be evaluated," they add.

If at all, it is de minimis.

The real point is the use of this techno-bacterio-babble to suggest that people get fat from their gut bacteria.

Bulls**t.

It remains absolutely impossible to gain weight in the absence of more Calories in than out.

Gut bacterial composition notwithstanding.

Hope For New Obesity And Diabetes Treatments From Mechanism That Turns White Fat Into Energy-Burning Brown Fat

No there isn't.

Columbia University Medical Center (CUMC) researchers have identified a mechanism that can give energy-storing white fat some of the beneficial characteristics of energy-burning brown fat. The findings, based on studies of mice and of human fat tissue, could lead to new strategies for treating obesity and type 2 diabetes. The study was published in the online edition of the journal Cell.

But it won't.

There is only one strategy that will lead to weight loss.

Fewer Calories in than out.

If you think that they will be able to control the relative proportions of white and brown fat in your body, and do it harmlessly before your overfatness sickens you, you are an idiot.

Recommendations From Guidelines on Obesity In Type 2 Diabetes Are Largely Consistent

As are the patients - they are consistently largely and portly and fatly.

...the German Institute for Quality and Efficiency in Health Care (IQWiG) published the results of a literature search for evidence-based guidelines for the treatment of obesity in type 2 diabetes. The aim of the report was to identify those recommendations from current guidelines of high methodological quality that may be relevant for a possible new obesity module in the disease management programme (DMP) for type 2 diabetes.

Diet, exercise and behavioural therapy generally advised

IQWiG found that the recommendations of the various guidelines for the treatment of people with type 2 diabetes who are also grossly overweight were more or less consistent: in general, alongside weight reduction, diet, exercise and behavioural therapy were also advised.

They (the recommendations) are also consistently ignored.

Sexual, Urological Disorders Linked to Waist Size

And oddly, they are not linked to small waist sizes.

For the first time in a comprehensive way, researchers have associated obesity in men, particularly large waist circumference (WC), with sexual and urologic dysfunction, in addition to metabolic effects.

Go figger.

Most Severely Obese Kids Have CV Risk Factors

Fat parents have fat kids.

About two-thirds of children and adolescents with severe obesity have at least one cardiovascular risk factor, such as elevated total cholesterol or triglycerides, high fasting glucose levels, or hypertension...

More nutritional child abuse. Kudos, fatsos.

Exposure To Magnetic Fields In The Womb Associated With Increased Risk Of Obesity In Childhood

This is it.

This is the key to fatosity and it offers a simple solution. Finally.

In-utero exposure to relatively high magnetic field levels was associated with a 69 percent increased risk of being obese or overweight during childhood compared to lower in-utero magnetic field levels, according to a Kaiser Permanente study that appears in the current online version of Nature's Scientific Reports.

Researchers conducted the prospective cohort study, in which participating women in Kaiser Permanente's Northern California region carried a meter measuring magnetic field levels during pregnancy and 733 of their children were followed up to 13 years, to collect clinically recorded information on growth patterns. On average, 33 weight measurements per child were collected.

Researchers noted a dose response relationship with increasing in-utero magnetic field levels being associated with further increased risk of obesity or being overweight. The observed association and supporting evidence provide the first epidemiologic findings that link increasing exposure to environmental magnetic fields, especially in-utero exposure, over the last few decades with the rapid rise in childhood obesity during the corresponding decades, according to the authors.

Clearly, the magnetic field causes attraction to Calories.

The solution?

Expose all pregnant women to the reverse polarity so their kids are repulsed from Calories.

Done.

MCI Linked to Social Isolation, Death

Fat people are more likely to be cognitively impaired.

Mild cognitive impairment (MCI) with memory loss, also known as amnestic MCI (aMCI), is linked to an increased risk for death. Furthermore, MCI with or without memory loss is linked to an increased risk for social isolation, new research shows.

Well, at least you'll have food to keep you company.

'Obese' Or 'Overweight' Are Hurtful Labels, Whereas Terms Like 'Large' Considered By Parents To Be Less Offensive

Fat parents have fat kids.

Poor, poor nutritional child abusing babies.

Are their fatso feelings hurt?

If doctors want to develop a strong rapport with parents of overweight children, it would be best if physicians used terms like "large" or "gaining too much weight" as opposed to the term "obese." These were findings recently published by medical researchers at the University of Alberta.

Geoff Ball, a researcher in the Faculty of Medicine & Dentistry with the Department of Pediatrics, worked with department colleagues Amanda Newton and Carla Farnesi to review articles about the important relationship between families and health professionals when it comes to addressing concerns about children's weight. Farnesi has since moved to Montreal where she will soon start her PhD at Concordia University. Their findings were recently published in the peer-reviewed journal, Pediatric Obesity.

They found the delicate balance was affected by: parents' preferences about language regarding obesity, how health professionals talked about weight, how care was delivered and parents' expectations.

"Health professionals probably shouldn't use terms like fat, chubby, overweight or obese," says Ball. "Terms that are more neutral, less judgmental and less stigmatizing should be used. Most of the time families will want that sensitive type of language. And that's what clinicians should want, too, because that's what families want."

Some parents felt blamed for their children's weight issues, while others found health professionals "rude and judgmental" or inattentive.

Which is why "F*ck you" is so appropriate a response to these fatsos.

It is a term that is universally understood, makes one's position clear and requires no need to remember how one tippy-toes around an issue.

There is much to be said for simplicity.

Canada's Food Guide Servings Misunderstood By The Public

It is okay. Serving size is useless, unless you can calculate the Calories.

Think you know what one serving of food looks like? You may want to think again, according to a new study from York University.

Many people overestimate the size of one serving of food as defined in Canada's Food Guide, so they may be overeating even if they believe they are being careful, according to a study by Jennifer Kuk, a professor in the School of Kinesiology & Health Science in York's Faculty of Health, and lead author Sharona Abramovitch, a former graduate student at York. The study was published online in the journal Applied Physiology, Nutrition and Metabolism.

Canada's Food Guide is an important tool used by many general practitioners to help their patients eat more healthfully, says Kuk, so it made sense to study whether people would be able to tell from the food guide if they are eating enough of the four food groups: vegetables and fruit, meat and alternatives, grain products, and milk and alternatives.

"What we found was that the way people estimate one serving is essentially how much they would normally eat at one time," says Kuk. "The majority of participants in the study inaccurately thought they would need to increase their food consumption by approximately 400 calories to meet recommendations in Canada's Food Guide. This suggests we either need to change the size of a serving in the Guide - which has remained almost the same since 1977 - or educate Canadians more about how much food they should be consuming in a day."

It is all about the Calories.

What this study does show that is of some value, is that people will always find a way to render a system useless or worse.

It also shows how bad the experts are at creating solutions to problems.

Do not follow expert diet advice.

Health Coaches To Help Fight Obesity? Could Be Cost Effective

Only if the rest of us don't have to pay for them.

Coaches have always had an important influence on improving athletic skills and guiding athletes to their greatest potential. Can a similar type of coach have the same influence on patients battling obesity?

According to the findings of a recent pilot study by researchers from the Miriam Hospital's Weight Control and Diabetes Research Center, health coaches can play an important role in weight loss.

Obesity is a serious and costly disease in the United States. According to the Centers for Disease Control and Prevention, one-third of American adults are obese. Obesity is not only a health problem, but also has severe impacts on the nation's health care system, costing millions of dollars every year.

In the first study of its kind, the volunteers who took part in a low-intensity behavioral weight loss program, and were supported by either a peer coach or a health professional coach, were found to have impressive results regarding weight loss (5% or more of their initial body weight).

Lead author Tricia M. Leahey, Ph.D., of The Miriam Hospital's Weight Control and Diabetes Research Center says:

"Although these findings are only preliminary, it's encouraging that lay health coaches successfully supplemented a less intensive, lower cost behavioral intervention and that their weight losses were actually comparable to those produced by professional coaches - something that could be critical in this changing health care landscape."

Health coaches serve as ongoing support, accountability, and provide information and promote behavioral change outside of treatment visits.

"Ongoing support" is a buzzterm for the fat who lost weight, will regain it.

Exercise Helps Reduce Depressive Symptoms In Heart Failure Patients

Two words - Anabolic Clinic (sm).

A new study, published in...JAMA, found that patients with chronic heart failure had modest reductions in symptoms of depression after 12 months of participating in exercise training, compared with usual care.

First, training, not exercise.

Second, it is clear that anabolic substances increase tolerance to physical activity in heart failure patients allowing them to derive even greater benefits.

Obesity Treatments Obstructed By Weight-Loss Clinic Drop-Out Rates

No mystery here.

Dieters are starved into failure.

See here, here, here, here and here.

More than 1.7 billion people worldwide may be classified as overweight and need appropriate medical or surgical treatment with the goal of sustainable weight loss. But for weight management programs to be effective, patients must complete them, states a study published in the Canadian Journal of Surgery (CJS) that analyzed drop-out rates and predictors of attrition within a publicly-funded adult weight management program.

Researchers from the Department of Surgery at the University of Alberta and the Centre for the Advancement of Minimally Invasive Surgery at the Royal Alexandria Hospital in Edmonton, Alberta, found that over a six-year period almost half (43%) of the patients of a weight-management clinic funded by Alberta Health Services dropped out of the program before achieving sustainable weight loss.

The program involves 6 months of primary care, including education on strategies for treating obesity, nutritional counselling, smoking cessation, physical activity and mental health assessment to identify untreated conditions, such as depression, that may be barriers to effective weight management. Some participants also undergo bariatric surgery.

In a group of patients who are motivated enough to participate in a program like this, a 43% drop-out rate is surprising. "Identifying the factors that predict attrition may serve as a basis for program improvement and further research," the authors state.

Among the patients included in the study, the drop-out rate was 54% in the group treated by medical management only and 12% in the group treated surgically. These drop-out rates are similar to those reported in other studies. "We speculate that patients willing to undergo the initial bariatric surgical procedure may be more committed to complete the program," the authors explain. They suggest that the substantial early weight loss associated with bariatric surgery may serve as additional motivation to continue in the program.

Younger patients and women were also more likely to drop out of the program.

"Further research is needed to clarify why surgical patients have lower attrition rates and how these factors can be applied to proactively decrease the drop-out rates and increase success," the authors state.

There is no need for "further research."

There is a need to change the doomed-to-fail diet advice of the "experts."