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Sunday, November 27, 2011

Neuron Transplants Can Repair Brain Circuits

This is not evidence that there is a problem with the brains of fat people.
A new study by Harvard University neuroscientist Jeffrey Macklis and colleagues suggests it is possible to transplant fetal neurons into a part of the mouse brain that does not normally generate new brain cells, and they will repair abnormal circuits. In this case, the researchers repaired a genetic defect that causes obesity, but that was not the goal of their work which was to establish proof of principle that transplanted neurons can integrate into existing faulty brain circuits and restore them...

The researchers, from Harvard University, Massachusetts General Hospital (MGH), Beth Israel Deaconess Medical Center (BIDMC) and Harvard Medical School (HMS) used mutant mice that had been genetically engineered to lack the receptor for leptin, a hormone that acts on brain cells in the hypothalamus to regulate metabolism and control body weight. Without this receptor, mice become morbidly obese and diabetic.
Nope, fat people do not lack the leptin receptor.

They lack self-control.

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