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Tuesday, July 20, 2010

For BP More Control Means Less Benefit in T2D

Type 2 diabetes is fat person diabetes.
Tight control of blood pressure to less than 130 mm Hg systolic does not improve major cardiovascular outcomes in diabetes patients with major coronary artery disease, researchers have again affirmed.

Compared with more standard 130 to 140 mm Hg control, tighter was not better for the composite rate of all-cause mortality, nonfatal MI, and nonfatal heart attack (12.6% standard versus 12.7% tight, P=0.24), found Rhonda M. Cooper-DeHoff, PharmD, MS, of the University of Florida in Gainesville, and colleagues.

Moreover, achieving tight control was associated with increased risk of death from any cause (11.0% versus 10.2%, P=0.06 over two years and 22.8% versus 21.8%, P=0.04 over seven years), they reported in the July 7 issue of the Journal of the American Medical Association.

However, these results run counter to clinical guidelines from the American Diabetes Association, American Heart Association, and seventh report of the Joint National Committee (JNC 7), which all recommend a target of less than 130/85 or 130/80 mm Hg for diabetes patients.

But the evidence does not support those recommendations, said co-author Carl J. Pepine, MD, also of the University of Florida in Gainsville.

"In fact, our data suggests that if the blood pressure is lowered to approximately 115 systolic there's hazard associated with it," he said in a video interview.
More evidence that they have no idea what they are talking about.

If you are fat and not too stupid to help yourself, get fit, because the people you expect will be your saviors are shooting in the dark.

Go here.

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