"Heart attacks and strokes the leading causes of death in the United States and other developed countries may have been rare for the vast majority of human history, suggests a study to be published in PLoS ONE on Tuesday, August 11...And so, the shelf life of yet another biomarker is in question.
Chronic inflammation, which may lead to damage of the arteries, is prevalent among the Tsimane. According to the study, the Tsimane also have unusually high levels of C-reactive protein, increasingly used in clinical settings to evaluate risk for cardiovascular disease.
Yet, despite these risk factors for heart attacks, the researchers found that the high levels of C-reactive protein were unrelated to risk of peripheral arterial disease (the hardening of plaque in the arteries).
In fact, peripheral arterial disease 'increases with age in every investigated population except the Tsimane,' according to the study. Among the Tsimane, not a single adult showed evidence for peripheral arterial disease (measured using the ankle-brachial blood pressure index)."
Still think they have any idea what they are talking about?
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