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Wednesday, August 12, 2009

Effect Of Gastric Bypass Surgery On Kidney Stone Disease

The effect is bad.
"UroToday.com - 'Those who cannot remember the past are condemned to repeat it.' (George Santayana in The Life of Reason 1905). One of the first unintentional human models created for calcium oxalate stone formation was in the obese patient who underwent a jejunal ileal bypass.

In this patient population, the risk of stone disease at 5 years after surgery rose to approximately 20%. In some patients, renal failure resulted. Given this situation, in 1979, the Food and Drug Administration declared a moratorium on jejunal ileal bypass.

Fast-forward 30 years. Enter the Roux-en-Y gastric bypass surgery for obesity. In this comparison of 4,639 patients undergoing this procedure vs. 4,639 nonoperated obese patients...

To be sure, these patients are at an increased risk of stone formation after their procedures. Appropriate dietary measures were recommended by the authors (increased fluid intake, low protein diet, low salt diet, normal calcium diet); however, recommending a diet to someone who has undergone an operative procedure for obesity seems futile at best. Are we rediscovering what we already knew and have we now sewn (sic) seeds that over time will lead to worsening urolithiasis and new cases of renal failure? Caveat emptor."
Yep.

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