"A team of scientists in the US found that mice lacking a gene that is involved with and controls enzymes that regulate energy production in cells became obese and insulin resistant even though they ate less and exercised more than their brothers and sisters.It is all about Calories in vs. Calories out.
The findings are the result of a study by Dr Rob Lewis of the Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, and 26 other researchers from various centers in the US. It was published in the journal Cell Metabolism on 4 November.
Lewis told the press that the genetically modified mouse, which they bred to lack a protein called Kinase Suppressor of Ras 2 (KSR2), was interesting because while it ate less and was more active than its normal brothers and sisters, it got fat."
If, for example, you burn fewer Calories for whatever reason, if you consume fewer Calories it will be impossible for you to gain weight and it will be possible for you to lose weight.
Period.
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