AACR: No Statin Benefit in Colon Cancer, Maybe Some Harm

Still think they have any idea what they are talking about?

Statins offer no protection against colorectal adenomas and might even increase the risk of the precancerous lesions with long-term use, according to a subset analysis of a large prevention trial.
Overall, statin users had a nonsignificant 24% increased risk of adenomas during five years of follow-up. However, the hazard jumped to almost 40% in patients who took statins for more than three years (P=0.024).

"Preliminary data suggesting that statins may prevent colorectal cancer are not supported by this prospective analysis of a subset," Monica Bertagnolli, MD, of Harvard, said at the American Association for Cancer Research meeting here. "More clinical data are needed to determine whether statins can actually increase adenoma risk, as this observational result was only significant in the subset of patients who were using statins for more than three years and who were also taking placebo."

Oops.