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Thursday, June 16, 2011

Biomarker Reality Fails to Match Hype

Still think they have any idea what they are doing?
Highly cited biomarker studies often report effect estimates that fall short in subsequent meta-analyses of the same associations between marker and disease, authors of a review concluded...

The findings from the review underscore the disparity between the hope and the reality of biomarker research, according to the author of an accompanying editorial.

"With few exceptions, most of these promises have yet to be fulfilled," wrote Patrick M.M. Bossuyt, PhD, of the University of Amsterdam, in the Netherlands.
What does work is fitness.

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