Rebound Acid Reflux with PPIs May Induce Dependence

Still think they have any idea what a safe drug is?

"Popular antacids known as proton pump inhibitors, or PPIs, may cause or aggravate the very acid-reflux symptoms they're used to treat, according to a new study.

After two months of taking esomeprazole (Nexium), 44 percent of healthy volunteers who started with no symptoms developed significant heartburn, acid reflux or dyspepsia, compared with 15 percent who took a harmless placebo, the scientists reported in the July issue of Gastroenterology.

Worse, this apparent "rebound" acid secretion could lead to dependence on the drugs, according to the research team led by Dr. Peter Bytzer of Copenhagen University in Denmark.

PPIs are among the most commonly prescribed drugs worldwide, with doctors in the United States writing 113.4 million prescriptions for the drugs last year, according to the health care information company IMS Health. The class includes drugs such as Prilosec, Nexium and Prevacid."

And some of these things moved from the prescription-only domain to the OTC realm.

You can bet that the IMHO malpractice of fat person diet drugs will continue to reveal more and more complications as time passes.

Really.

Better to lose the weight properly and on your own than having drugs involved.